Search results for "Test procedures"
showing 10 items of 12 documents
Oral Solid Dosage Form Disintegration Testing — The Forgotten Test
2014
Since its inception in the 1930s, disintegration testing has become an important quality control (QC) test in pharmaceutical industry, and disintegration test procedures for various dosage forms have been described by the different pharmacopoeias, with harmonization among them still not quite complete. However, because of the fact that complete disintegration does not necessarily imply complete dissolution, much more research has been focused on dissolution rather than on disintegration testing. Nevertheless, owing to its simplicity, disintegration testing seems to be an attractive replacement to dissolution testing as recognized by the International Conference on Harmonization guidelines, …
Immunity of a Virtual Instrument to conducted electromagnetic disturbances
2004
In the paper the performances of the Virtual Instruments under conducted electromagnetic disturbances are investigated, in order to find out if and how their metrological characteristics change with respect to the ones measured in absence of electromagnetic threats. The analysis is carried out by means of experimental tests, subjecting the AC power port of the systems under test to the conducted disturbances considered by the IEC-61326 standard and following the test procedures prescribed in the IEC-61000-4-series standards. The results show that the tested measurements instruments are sufficiently immune to these disturbances, since no variations of the distinctive parameters have been obs…
The future use of structural composite materials in the automotive industry
2007
The automotive industry's use of structural composite materials began in the 1950s. Since those early days, it has been demonstrated that composites are lightweight, fatigue resistant and easily moulded to shape in other words, a seemingly attractive alternative to metals. However, there has been no widespread switch from metals to composites in the automotive sector. This is because there are a number of technical issues relating to the use of composite materials that still need to be resolved including accurate material characterisation, manufacturing and joining. This paper reports the findings of a recent European initiative that examined the future use of composite materials in the aut…
Improvements of General Multiple Test Procedures for Redundant Systems of Hypotheses
1988
In dieser Arbeit wird untersucht, welche Verscharfungen allgemeiner multipler Testprozeduren moglich sind, wenn die Kenntnis von „Redundanzen“ (logischen Abhangigkeiten) im Hypothesensystem ganz oder teilweise ausgenutzt wird. Fur den Fall gleicher Gewichtung der Elementartests werden mehrere verbesserte „statische“ Prozeduren angegeben, unter denen sich auch die „MSRB-Prozedur“ von Shaffer (1986) befindet. Last man auch ungleiche Gewichtung zu, so erhalt man vier verschiedene „dynamische“ Verbesserungen der Prozedur von Holm (1979), die in aufsteigender Reihenfolge immer trennscharfer, aber auch immer rechenaufwendiger werden. Es werden praktikable Algorithmen vorgestellt, die in einem ent…
ATLAS TileCal Read Out Driver production
2007
The production tests of the 38 ATLAS TileCal Read Out Drivers (RODs) are presented in this paper. The hardware specifications and firmware functionality of the RODs modules, the test-bench and the test procedure to qualify the boards are described. Finally the performance results, the temperature studies and high rate tests are shown and discussed.
Test procedures for obtaining representative extracts suitable for reliable in vitro toxicity assessment of paper and board intended for food contact.
2009
International audience; This paper describes the use of a suite of extraction procedures applicable to the assessment of the in vitro toxicity of paper/board samples intended for food-contact applications. The sample is extracted with ethanol, water, or exposed to modified polyphenylene oxide (Tenax) for fatty, non-fatty and dry food applications, respectively. The water extracts are directly suitable for safety assessment using in vitro bioassays. The ethanol extracts of the paper/board and of the exposed Tenax require pre-concentration to give acceptable sensitivity. This is because the in vitro bioassays can tolerate only a small percentage of added organic solvent before the solvent its…
Multiple testing of pairs of one-sided hypotheses
1986
Two-sided test procedures fork real parameters should point out in the case of rejection whether the left or the right alternative can be assumed. This sets up a multiple testing problem fork pairs of one-sided hypotheses. Holm's (1979, Scandinavian Journal of Statistics 6:65–70) sequentially rejective test provides a solution the critical levels of which are slightly improved. Considerable improvement is obtained when the hypotheses are redefined to be disjoint in pairs.
Sequentially Rejective Test Procedures for Detecting Outlying Cells in One- and Two-Sample Multinomial Experiments
1985
For multiple testing of multinomial models in the case of one or two samples we propose using test procedures based on the principle described by MARCUS, PERITZ and GABRIEL (1976). These methods are based in each step of the sequentially rejective strategy on tests which exhaust the full α level (i.e. which are not conservative). The tests can be performed in a finite or asymptotic version.
Improvements and Modifications of Tarone's Multiple Test Procedure for Discrete Data
1998
Tarone (1990, Biometrics 46, 515-522) proposed a multiple test procedure for discrete test statistics improving the usual Bonferroni procedure. However, Tarone's procedure is not monotone depending on the predetermined multiple level a. Roth (1998, Journal of Statistical Planning and Inference, in press) developed a monotone version of Tarone's procedure. We present a similar procedure that is both monotone and an improvement of Tarone's proposal. Based on this extension, we derive a step-down procedure that is a corresponding improvement of Holm's (1979, Scandinavian Journal of Statistics 6, 65-70) sequentially rejective procedure. It is shown how adjusted p-values can be computed for the …
Global and multiple test procedures using ordered p-values—a review
2004
This paper reviews global and multiple tests for the combination ofn hypotheses using the orderedp-values of then individual tests. In 1987, Rohmel and Streitberg presented a general method to construct global level α tests based on orderedp-values when there exists no prior knowledge regarding the joint distribution of the corresponding test statistics. In the case of independent test statistics, construction of global tests is available by means of recursive formulae presented by Bicher (1989), Kornatz (1994) and Finner and Roters (1994). Multiple test procedures can be developed by applying the closed test principle using these global tests as building blocks. Liu (1996) proposed represe…